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Finasteride (Proscar®) is a 5-alpha reductase inhibitor. The first 5-alpha reductase inhibitor used in the treatment of prostate cancer was a drug called finasteride. This drug was first approved by the FDA in 1992 and has since been prescribed for other indications.

Finasteride is the only 5-alpha reductase inhibitor approved by the FDA for the treatment of benign prostatic hyperplasia (BPH). The recommended starting dose is one 5-alpha reductase inhibitor, then another 5-alpha reductase inhibitor, and then a second 5-alpha reductase inhibitor. Finasteride is effective in the treatment of both BPH and prostate cancer.

The drug is marketed by the following companies: Proscar, Proscar Propecia, Proscar Dutasteride, Finasteride Generic Drug, Finasteride (Proscar®) Generic Drug, Proscar (Proscar®) Generic Drug Propecia, Proscar (Proscar®) Generic Drug Propecia Finasteride Generic Drug Proscar Propecia

Finasteride was the first 5-alpha reductase inhibitor to be approved by the FDA for the treatment of BPH and prostate cancer. It was first approved by the FDA in 1992, and has since been prescribed for other indications.

Finasteride (Proscar®) and Other Prostate Cancer Drugs

Finasteride is available in two doses: 1 mg daily for 5 years and 5 mg once daily for 1 year. The 5-alpha reductase inhibitor finasteride is effective at preventing the progression of BPH to the enlargement of the prostate. Finasteride is also effective in reducing the incidence of acute and chronic prostate cancer.

Finasteride is the only 5-alpha reductase inhibitor approved by the FDA for the treatment of benign prostatic hyperplasia. It is used by millions of men each year for the treatment of male pattern hair loss.

The most common side effects of finasteride include decreased libido, sexual dysfunction, impotence, and ejaculation disorders. These adverse effects are most commonly reported during the first few months of treatment with finasteride, and may decrease by approximately half the amount if continued. The most common side effect is decreased sexual desire.

Finasteride is not approved for use in women. Men who are pregnant or may become pregnant should not handle crushed or broken tablets of finasteride.

Finasteride can cause serious side effects, including vision problems and changes in vision. These side effects are more likely to occur in men who are taking finasteride than in those who are not.

Finasteride is also not approved for use in children under 18 years of age. The side effects reported in children and adolescents include: decreased sexual ability, delayed puberty, inability to become erect, and decreased ejaculatory volume.

The most common side effects of finasteride are decreased libido, impotence, and sexual dysfunction. If these side effects are not treated, they may result in prostate surgery. If finasteride is continued, it may cause serious side effects such as: decreased libido, delayed puberty, inability to become erect, and decreased ejaculatory volume.

Finasteride can interact with other medications, including:

  • Alpha-blockers, including Prostate-Specific Antagonists (PSA) and Erectile Dysfunction Medications (EDM)
  • Sulfonylureas, including medications used to treat diabetes and prostate enlargement.
  • Aliskiren.

Finasteride may also interact with certain medications. It is not known if finasteride can increase the risk of a drug interaction when taken with certain medications. In addition, the effect of finasteride on the heart rhythm may be decreased in people who take certain medications.

Finasteride is only available as an oral tablet.

The safety of finasteride has not been established for use in children younger than 6 years of age.

Treatment of Benign Prostatic Hyperplasia

Benign prostatic hyperplasia (BPH) is the most common cause of urinary retention in the US. It occurs when the prostate gland enlarges, and the bladder becomes enlarged. If BPH is not treated, the prostate gland will eventually grow out.

How to use FINAX 1MG TABLET

Take Finax 1mg Tablet as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

How to Use Finax Tablet:

Take one tablet daily, preferably at the same time each day. Follow your doctor's instructions and do not exceed the recommended dosage.

Finax dosage for hair loss:

  • The usual dosage of Finax 1mg for hair loss is one tablet per day, as prescribed by a doctor
  • It is typically taken at the same time daily, with or without food
  • Consistent use for at least 3-6 months is required to see noticeable results
  • It is important not to exceed the recommended dose and to follow your doctor's advice to avoid potential side effects. For detailed guidance, consult a healthcare professional.

What If I Forget To Take A Dose of Finax?

If you miss a dose of Finax 1mg, take it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed tablet. Consistent daily use is essential for optimal results in managing hair loss. Always consult your doctor for specific advice regarding missed doses.

Finax: Long-Term Use and Health Risks:

Long-term use of Finax tablets may cause potential side effects, such as decreased libido, erectile dysfunction, or depression, may persist or appear over time.

Regular follow-ups with a doctor are essential to monitor your health and assess continued suitability.

Long-term benefits, like sustained hair regrowth and reduced hair loss, can be seen with consistent use, but stopping the medication may reverse results.

Studies suggest that prolonged use of finasteride may be associated with health risks, including non-alcoholic fatty liver disease (NAFLD), insulin resistance, type 2 diabetes mellitus (T2DM), dry eye disease, and potential kidney issues.

Finax Use in Women:

Finax (finasteride 1mg) is not typically recommended for women, particularly during pregnancy, as it can cause birth defects in male fetuses. It may be prescribed in some cases for women with severe hair loss (such as post-menopausal women), but under strict medical supervision. Women are often advised to explore other treatments, like minoxidil, for hair regrowth. Always consult a healthcare provider before considering Finax for any use in women.

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Still notable side effects of Finax include increased libido, erectile dysfunction, and ejaculatory delay in women, which may not become apparent in time. It may increase risk for nausea, vomiting, heart problems, heart attack, stroke, and liver disease in individuals.

Finax Use in Children:

However, Finax is not usually recommended for use in children. It may be prescribed in some cases in combination with a reduced-calorie diet and activities of dailyUsage:

Finax Dosage:

Finax 1mg are typically prescribed by healthcare professionals to patients with severe hair loss or those past medical advice should be used uncommon. In some cases, 1mg may be used even for a 3-month period before experiencing noticeable results.

Finax Interactions:

It's important to consult a patient assistance program before considering the use of finasteride for specific medications it’s not safe to use alongside:

  • isosorbide mononitrate tablets ( like the generic) at the same time as isrialaunide tablets ( the generic)
  • cisplatin
  • other hormonal treatments for hair loss
  • antifungal medications such as cisapride and pediatric antifungal medications such as ketoconazole.’s.’s.’s
  • heparin anticoagulants such as warfarin for high-blood pressure treatments.

1. Introduction

Finasteride (brand name Propecia®, brand name Proscar®), a highly effective medication that is widely used to treat and promote hair loss, is among the most prescribed medications. The efficacy of Finasteride has been well documented and is primarily attributed to its inhibition of an enzyme that converts testosterone into dihydrotestosterone (DHT).

In this study, we investigated the effect of Finasteride on hair growth in a rat model. Rats were administered 1 mg/kg/day finasteride intraperitoneally for 3 weeks, starting at day 5. At the end of the experiment, the rats were killed, and their hair loss, and the hair density were determined. Finasteride treatment significantly inhibited the hair growth and reduced the hair loss in rats treated with finasteride in both the hair loss and hair density experiments. Furthermore, finasteride treatment prevented the development of hyperplasia of the hair follicles in the hair loss and hair density experiments. These results indicate that Finasteride may inhibit hair growth and promote hair loss by reducing the expression of the genes involved in follicle development and the formation of hair follicles.

Furthermore, our study confirmed that Finasteride is a more effective treatment for the prevention of the progression of hair loss in men with androgenetic alopecia (AGA). In this study, the effects of finasteride on hair growth in male rats were evaluated using the rat model. Finasteride administration significantly inhibited the development of hyperplasia and the prevention of the development of follicular miniaturization of the follicular layer of the hair follicle. Furthermore, finasteride treatment prevented the progression of hyperplasia and the prevention of follicular miniaturization in the rat model.

2. Materials and methods

2.1. Protocol and administration

Rats received finasteride (1 mg/kg) or vehicle (control) by gavage from Day 1 to Day 5, and then the rats were housed individually in an individual cage at regular intervals throughout the experiment. The rats were fed a normal diet and water. The rats were permitted to acclimatize to the experiment for at least 1 week before starting the experiments. After acclimatization, the rats were randomly divided into 3 groups (n = 6 for each treatment group):

  • Group I (control) received finasteride (0.5 mg/kg) or vehicle (1 mg/kg)
  • Group II (Finasteride) received finasteride (1 mg/kg) or vehicle (0.5 mg/kg)

The experimental groups were administered finasteride intraperitoneally at a dose of 1 mg/kg or 0.5 mg/kg for 3 weeks starting at day 5, respectively, and then finasteride treatment for 3 weeks.

2.2. Growth and morphometric analyses

The growth of the hair follicles and the thickness of the hair follicle, the follicle size and the thickness of the hair follicle, and the hair density were evaluated using the in vitro growth assay. The growth of hair follicles and the thickness of hair follicle, the follicle size and the hair density, and the hair thickness were analyzed using the in vivo growth assay.

2.3. Scanning Electron Microscopy (SEM) analysis

The human dermal papillae (HP) cells were stained with 1% crystal violet and then evaluated in three randomly selected fields at 100× magnification. The images were recorded with a scanning electron microscope (JEOL JEM-2100; JEOL Corporation, Tokyo, Japan) and analyzed using the ImageJ v1.48 software ( version 12.0.0.1).

3. Results and Discussion

3.1.

The results showed that the experimental group treated with finasteride showed no significant difference in the growth of hair follicles compared with the control group in the growth of hair follicles, the thickness of the hair follicle and the hair density. Furthermore, the follicle size and the hair density were all significantly decreased in the experimental group when compared with the control group. In addition, the hair density was significantly reduced in the experimental group compared with the control group. These results indicate that Finasteride is a more effective treatment for the prevention of the progression of hair loss in men with androgenetic alopecia (AGA).

3.2.